Technology Platforms

MassARRAY System 

The MassARRAY System is a non-fluorescent detection platform utilizing mass spectrometry to accurately measure PCR-derived amplicons. Mass spectrometry, coupled with end point PCR, enables highly multiplexed reactions under universal cycling conditions to provide accurate, rapid, and cost-effective analysis. The MassARRAY System offers a unique solution for targeted genetic testing with limited input material.

The MassARRAY System is an open platform that empowers laboratories to perform a variety of DNA and RNA analysis. The following applications are currently available:

Genotyping and mutation detection

Ultrasensitive detection

Methylation analysis

Gene expression analysis

Pathogen detection

Choose one of our predesigned panels, use our Assay Design Suite software to design your own tests, or take advantage of custom assay development services from Assays by Agena.

Ion Proton System

The Ion Proton™ System is the first benchtop sequencing system capable of human-scale genome, exome, or transcriptome sequencing in a few hours—with DNA-to-variants called in a single day.

Features of the Ion Proton™ System:

• Fastest high-throughput next-generation sequencing workflow with the fastest sequencing run-times of 2–4 hours on the Ion PI™ Chip

• Highest number of complete sequencing runs per week, with a simple and automated workflow (when used with the Ion OneTouch™ 2 System)

• Simple semiconductor sequencing workflows with robust and simple hardware that can be relied upon—no cameras, no optics, and no lasers

• Scalable, high throughput sequencing capabilities enabling up to 200-base single reads and flexible library options (e.g., fragment gDNA, targeted/exome, RNA)

• Small benchtop footprint and mounting capability (with optional rack) (two Ion Proton™ systems per rack), to deliver the only benchtop genome center

• Low-cost platform and attractively priced semiconductor chips and reagents for a range of applications

• Proven Ion semiconductor sequencing requires no complex optics and employs natural nucleotides to deliver highly accurate variant detection, uniformity of coverage, and sensitivity to detect low frequency variants

• Range of fast and simple library solutions and kits with low-input requirements for a variety of applications, such as genomic sequencing, exome sequencing, sequencing sets of genes, and RNA sequencing

• Complete end-to-end solution from base calls to variants with the Proton™ Torrent Server and Torrent Suite Software v3.0

• Simple and integrated tools for tertiary data analysis with Ion Reporter™ Software for DNA variation analysis across single, paired, or trio samples

QuantStudio 7 Flex Real-Time PCR System

With a simplified workflow, intuitive software, automation capabilities, and touch-screen interface, the QuantStudio™ 7 Flex system offers exceptional reproducibility with minimal well-to-well and instrument-to-instrument variation.

Features of the QuantStudio™ 7 Flex Real-Time PCR System include:

Increased application versatility through the accomodation of 4 different block types

Compatible with over 8 million TaqMan™ assays for gene expression, genetic variation, gene regulation, or protein expression experiments

The intelligent design of the QuantStudio™ platform combined with Applied Biosystems™ instrument reliability and accuracy

Easy-to-use software, responsive touch-screen, automation capabilities, and effortless block exchange without the need for any tools

The QuantStudio™ 7 Flex system accommodates the interchange of a 96-well, 96-well Fast, 384-well, or TaqMan™ array card block. The system is delivered with one block type (a 384-well block in this case)..

Accomplish More, Faster

Run hundreds of real-time PCR reactions effortlessly using TaqMan® Array 384-well microfluidic cards. And when integrated with the Twister® Robot Automation Accessory (available separately), the QuantStudio™ 7 Flex system maximizes your throughput capabilities.

High Application Versatility

Simple workflows, reliable assays and reagents, multiple formats, and intuitive software are available for a broad range of applications, including gene expression, genetic variation, gene regulation, High Resolution Melt (HRM), and Protein Thermal Shift™ experiments.

Results You Can Trust

Improved well-to-well and instrument-to-instrument data accuracy is achieved with the OptiFlex™ system, which features 6 decoupled excitation and emission filter channels with 21 filter combinations for maximum multiplexing and chemistry flexibility.

Sensitive Data Analysis

Detect changes in target quantity as small as 1.5-fold in single-plex reactions and obtain 10 logs of linear dynamic range.

3730xl DNA Analyzer

The 96-capillary 3730xl DNA Analyzer is the Gold Standard for high throughput genetic analysis. Use this for DNA fragment analysis applications such as microsatellites, AFLP, SNP analysis, mutation detection and traditional DNA sequencing. Get the highest quality data at a low cost per sample.

Higher optical sensitivity and advanced polymers enable you to obtain higher-quality sequencing data for less.

Multiple automation features decrease costly human errors.

Optimized polymers increase your productivity without compromising your results.

Perform a wide variety of sequencing and fragment analysis applications including resequencing, microsatellite analysis, AFLP, LOH, SSCP, SNP screening and SNP validation.

Illumina iScan System

A cutting-edge array scanner that supports rapid, sensitive, and accurate imaging of Illumina

BeadChips for exceptional genetic analysis results.

Highlights

• Exceptional Data Quality

Proven Infinium® assays produce high call rates and provide

exceptional coverage

• High Sample Throughput

Fast optical scanner dramatically reduces scan times, while

optimized automation features maximize output

• Flexible Configuration

Multiple formats, applications, and automation options

Nucleic Acid Extraction System

The Nucleic Acid Extraction System is an easy-to-use benchtop instrument that enables hands-free automation of the nucleic acid extraction process for contaminant and impurity testing. The instrument uses the established PrepSEQ® nucleic acid extraction chemistry for quantitative recovery of DNA and RNA from diverse samples types, including cell culture, raw material (i.e., serum), and in-process downstream purification samples such as column purification or bulk drug substance (BDS) samples.

Key Product Features:

• Time-saving, cost-effective DNA extraction for mycoplasma, MMV, vesivirus, and residual DNA quantitation

• Quantitative and reproducible recovery of DNA from complex samples

• Out-of-the-box automation with prefilled PrepSEQ® Express™ cartridges and ready-to-run protocols

• Closed system minimizes the risk of contamination

• Ideal for in-process testing of contaminants and impurities